Working in the Professorial Advisory Unit of The George Institute, Mark is also a Chair of Statistics, Faculty of Medicine, Imperial College of London and Adjunct Professor of Epidemiology at Johns Hopkins University.

He is the author of 400+ peer-reviewed publications and two textbooks on statistical methods in medical research, one of which had its third edition published in January 2014. He also has extensive experience in student teaching, postgraduate supervision and mentoring including 14 PhD and 19 MSc students successfully completed. He has given training workshops in Korea and Thailand and has taught at least 25 other research training courses. 

Mark served on the governing council of the Institute of Statisticians and the Royal Statistical Society (RSS) and is currently a fellow of the RSS, the European Society of Cardiology, the New York Academy of Medicine and the Royal Society of Medicine.